Reducing stress in daily life can help some people live for up to 150 years, researchers have found.
New York state’s Roswell Park Comprehensive Cancer Center in Buffalo and Singapore-based biotech company Gero have discovered a direct link between aging and the ability to cope with stress.
The study, “Longitudinal analysis of blood markers reveals progressive loss of resilience and predicts human lifespan limit” confirmed subjects, who recovered well from stressful situations, tended to live longer and enjoy better quality of life.
“The investigation shows that recovery rate is an important signature of aging that can guide the development of drugs to slow the process and extend healthspan,” Harvard Medical School genetics professor David Sinclair said in a statement.
In some exceptional cases, those with very good work-life balance could even live for as long as 150 years.
“If the [human resilience] trend holds at later ages, the extrapolation shows a complete loss of human body resilience, that is the ability to recover, at some age around 120 to 150 years old,” study author Timothy Pyrkov said in the statement.
This estimate is based on a variety of health factors, including not suffering from any major chronic diseases that could affect human body resilience.
“As we age, more and more time is required to recover after a perturbation and, on average, we spend less and less time close to the optimal physiological state,” Pyrkov said.
The research team spent more than three years collecting and using artificial intelligence, blood tests, and physical activity data from volunteers based in the United States and the United Kingdom.
Test subjects showed biological age is linked to stress, lifestyle, and chronic diseases. Resilience depended on how quickly someone returned to normal after responding to a stressor.
The study found a 40-year-old patient needs two weeks of rehabilitation to recover, while an 80-year-old needs six weeks of rehabilitation.
Researchers concluded the 120 to 150-year lifespan is an “absolute limit” for how long humans can live without any stressor or chronic disease.
However, the likelihood of someone experiencing no stressor or chronic disease is very low. Even the healthiest participants were susceptible to the same fundamental rules of aging, according to the study, which was published in the Nature Communications scientific journal on May 25.
The study also found no “strong life extension” can be achieved through preventing or curing diseases.
“Aging in humans exhibits universal features common to complex systems operating on the brink of disintegration,” Gero co-founder and CEO Peter Fedichev said in the statement.
“This work is a demonstration of how concepts borrowed from physical sciences can be used in biology to probe different aspects of senescence and frailty to produce strong interventions against aging,” he added.
These findings suggest a variety of widely publicized biohacking and age-defying techniques do not actually extend the longevity of humans. Patients only appear to look younger after treatment.
Rastegar Property Company founder Ari Rastegar recently claimed stem cell therapy and meditation in a hyperbaric chamber helped him return his body to the state of a 5-year-old child, according to the New York Post.